Engineering HSV Vectors to Enable Delivery of Large and Complex Therapeutic Genes
About this Event
1120 NW 14th St, Miami, FL 33136
Join us on March 12th for a presentation by Dr. Selene Ingusci, Ph.D., Research Instructor, Department of Microbiology & Molecular Genetics, University of Pittsburgh. The presentaton is in-person at CRB-1270 Conference Room.
Presentation Summary:
- Engineering high-capacity HSV vectors to unlock gene therapies beyond conventional size limits.
- Rewriting epigenetic control to resist host-mediated silencing and sustain long-term activity
- Enabling new therapeutic strategies across diverse disease contexts.
Learning Objectives:
By the end of this presentation, participants will be able to:
Explain the structural and functional difference between replication-defective HSV vectors and conventional systems. Evaluate how delivery platform design shapes therapeutic potential and long-term expression. Discuss the potential therapeutic advantages of delivering full-length genes using large-payload viral platforms. Evaluate translational considerations including tissue tropism, re-dosing potential, and immune context. Define the principles required to build next-generation, durable gene therapy
Light refreshments will be served on a first come, first served basis.
Please RSVP Lina.Gonzalez81@med.miami.edu to ensure your spot!
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